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Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M

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Patients may also misinterpret dosage instructions or struggle with proper measurement using syringes

Targeting metabolic vulnerabilities in specific macrophage subsets, such as limiting ferroportin-mediated iron export in M2 TAMs or enhancing ACSL4-dependent lipid peroxidation in inflammatory TAMs, may shift the TME toward a ferroptosis-permissive state

He has created a library of DPP-IV resistant peptides that bind at the receptor sites

Dose escalation should proceed according to FDA-approved titration schedules, typically every 4 weeks, though individual tolerance may necessitate slower progression