The activity of GCL, the rate-limiting enzyme for GSH synthesis, was upregulated in neurons co-cultured with GSH-depleted astrocytes, but the neuronal GSH levels were not increased [47]
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Rodriguez MC, Rosenfeld J, Tarnopolsky MA: Plasma malondialdehyde increases transiently after ischemic forearm exercise
Clinical trials have demonstrated that nausea, vomiting, diarrhoea, and abdominal discomfort are amongst the most commonly reported adverse reactions, particularly during the initial weeks of treatment or following dose escalation
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