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There is an increased risk for diabetic retinopathy complications in patients with a history of diabetic retinopathy at baseline compared to patients without a known history of diabetic retinopathy

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26 DNA damage or mutations develop to a certain extent, which exceeds the limit of self-repair, contributing to in situ carcinoma, where the pathological cells are confined within the ducts but have not yet invaded the surrounding tissues

Black box warnings are required by the FDA when there is a serious risk of harm to patients

Small HSPs as first responders to proteotoxic stress In contrast to HSP70 and HSP90, small heat shock proteins do not actively refold misfolded proteins