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Wegovy or Zepbound should not be used by people with a personal or family history of medullary thyroid carcinoma, MEN 2, or a prior serious hypersensitivity reaction to the specific medication or its ingredients

Researchers designing longer-duration studies should anticipate continued weight reduction beyond week 48 in subjects who tolerate the maximum retatrutide dose, and should plan follow-up biomarker assessments accordingly

Source: Advanced Bionutritionals

Eligibility varies based on personal health factors and clinical judgment