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Approximately 10% of the worlds population has severe periodontitis (ODowd et al., 2010)

References: [1] Camillerapp C, Mayfield D B, Papineni S, et al

Another major challenge lies in achieving effective CNS concentrations of TNF inhibitors, as many current compounds have limited permeability across the bloodbrain barrier

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Variations in yield were attributed to the influence of different reaction setups, reaction scales, or challenging purifications

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