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GHK-Cu (glycyl-L-histidyl-L-lysine complexed with copper 2+) is one of the most evidence-supported regenerative peptides available in cosmetics, with peer-reviewed data spanning collagen synthesis, gene-expression modulation, wound healing, and skin laxity

The compound has been studied in trials lasting up to 68 weeks, which provides useful medium-term data but leaves questions about effects beyond 2 years of continuous use

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Studies suggest it can block the NF-B pathway and reduce inflammatory cytokines like TNF- and IL-6 without causing skin darkening, making it a potentially safe option for systemic use

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Diese Wirkungen werden seiner Wirkung auf das NO-System zugeschrieben, die eine Anpassung des Geftonus an die physiologischen Bedingungen ermglicht