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doi: 10.3945/ajcn.2009.28095 400 HsuchouHPanWKastinAJ

These coactivators generally orchestrate with DNA-bound transcription factors, such as nuclear respiratory factors (NRF1, NRF2), estrogen-related receptors (ERR, ERR, and ERR), and myocyte enhancer factor 2 (MEF2) to drive the expression of target genes

However, observed weight gains were marginally lower than those seen with the comparator medications in the clinical studies [54, 55]

Unlike traditional weight loss methods, this triple-receptor agonist maintains its appetite-suppressing and metabolic effects over time

One of the primary challenges is optimizing antioxidant therapies

Class I deficiencies are the most severe and cause chronic hemolysis