Both can lead to rapid weight loss
Stage 4: Functional Deficiency Severe complications such as B12 deficiency anaemia, nerve damage, and cognitive decline, and common symptoms like: Constant tiredness or fatigue Pale or yellowish skin Numbness or tingling in hands and feet Difficulty walking or balance issues Mood swings, irritability, or depression Memory problems or confusion B12 deficiency hair loss reversible if treated early Swollen tongue or mouth ulcers If left untreated, the effects of vitamin B12 deficiency can include permanent nerve damage and increased risk of heart disease due to high homocysteine levels
I feel like those people need to be excluded outright

In the same study, Beyond the scale with Wegovy HD 1 Patients taking Wegovy HD pen 7.2 mg experienced improvements across most cardiometabolic risk factors Confirmatory secondary end points: Change from baseline to week 72 in 1 : Waist circumference: 5.6-inch reduction 2.2-inch reduction with placebo Supportive secondary end points: Change from baseline to week 72 in 1 : Lipid profile: Total cholesterol 3.4% reduction 4.0% reduction with placebo LDL 3.5% reduction 4.8% reduction with placebo HDL 9.5% increase 0.5% decrease with placebo Triglycerides 16.4% reduction 0.9% reduction with placebo Systolic blood pressure: 10.1 mm Hg reduction 4.8 mm Hg reduction with placebo Diastolic blood pressure: 4.5 mm Hg reduction 1.8 mm Hg reduction with placebo A1c: 0.3% reduction 0% change with placebo Safety end point: Change in 1 : Heart rate: 0.5 bpm increase 0.6 bpm reduction with placebo Wegovy is not indicated to treat hypertension, type 2 diabetes, or dyslipidemia

[153] There is evidence that for elderly people, physicians often repeatedly prescribe and administer cyanocobalamin injections inappropriately, evidenced by the majority of subjects in one large study either having had normal serum concentrations or having not been tested before the injections
Of particular interest to pain medicine physicians are Medicare payment changes for epidural steroid injections (ESI)