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Furthermore, extract from the flowers of Opuntia ficus-indica (prickly pear) has been shown to inhibit the activity of 5-alpha reductase, the enzyme responsible for converting testosterone into DHT (Jonas 1998)

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PT-141 , Bremelanotide , was derived directly from MT-II through C-terminal amide hydrolysis, producing a compound that retains the cyclic heptapeptide structure and MC3R/MC4R pro-sexual activity while reducing MC1R-mediated tanning

Ghosh P, Fontanella RA, Scisciola L, Pesapane A, Taktaz F, Franzese M, et al

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