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Participants were randomly assigned to receive either a once-weekly subcutaneous semaglutide or a placebo for 68 weeks in combination with lifestyle intervention

[6] [18] The standard titration schedule begins at 0.25 mg once weekly for four weeks (an initiation dose not intended for glycemic control), followed by escalation to 0.5 mg weekly

Understanding the timing and nature of side effects helps in managing expectations and seeking timely medical advice

The SURMOUNT-1 trial, also in the New England Journal of Medicine, studied tirzepatide in adults with obesity or overweight without type 2 diabetes

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Unfortunately, the same market forces driving demand incentivize unscrupulous individuals and companies to purchase raw materials from less reputable sources as well as cut corners on sterility, potency, and purity