The limma R software package (adjusted p 1) was used to screen differentially expressed genes (DEGs)
doi: 10.16438/j.0513-4870.2020-1246 30 LimYJSidorNATonialNCCheAUrquhartBL
Schulich School of Medicine Clinical Investigator Fellowship to KD
doi: 10.3390/antiox10020317 53 YanRXieELiYLiJZhangYChiXet al
a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation
Glutathione is the anchor for brightening: the bodys master antioxidant inhibits tyrosinase, the enzyme that drives melanin production, which is the mechanism behind its use as a brightening and antioxidant support, not a disease treatment