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Acknowledgments The authors acknowledge Consejo Nacional de Humanidades, Ciencia y Tecnologa (CONAHCYT) by the fellowship to BG-F (563011) and ML-S (658080)

Some practitioners recommend front-loading protocols, where men use 5-7.5mg for the first week, then reduce to maintenance doses of 2-2.5mg weekly

If youre unsure whether your progress is expected or concerning, talking with your provider is the best way to get clarity and decide what makes sense next

When the drugs were not solubilised, the solutions were heated up to 80 C and stirred for 2 h

If you had borderline low testosterone before starting treatment, consider testing levels again at weeks 16 and 32

Sperm are produced continuously in the testicles through a process called spermatogenesis, which takes approximately 74 days from start to finish