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They also represent the best cases, not the average case

doi:10.1016/j.peptides.2011.02.011 61

Pediatric obesity remains under-served, despite Wegovy adolescent approval in 2022

Novo Nordisk and Eli Lilly continue to dominate., Although Pfizer discontinued its in-house oral GLP-1 candidate danuglipron in April 2025 following a liver-injury signal, it has doubled back into obesity and GLP-1 with its multi-billion-dollar acquisition of Metsera

Objective: Glucagon-like peptide-1 (GLP-1) is secreted from enteroendocrine cells and exerts a broad number of metabolic actions through activation of a single GLP-1 receptor (GLP-1R)