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Before randomization, fasting blood glucose concentration was measured (EML 105 analyzer, Radiometer Medical A/S, Copenhagen, Denmark), and eligible individuals were randomized to receive two of three possible treatments (liraglutide 1.8 mg, 3.0 mg, or placebo)

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However, the reaction catalyzed by the key enzyme DAEase is reversible, and the conversion rate is low, which leads to a high price for the resulting D-allulose