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Experimental evidence showed that the lipid peroxidation product 4-HNE, at 0, 5, 10, 20, 30, and 50 M, induces a dose-dependent decrease in meiotic competence during in vitro oocyte maturation, as well as aneuploidies in germinal vesicle (GV) oocytes from 20 M of 4-HNE (Mihalas et al

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Vitamin B 12 is not present in foods of plant origin, but is abundant in foods of animal origin

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As such, a more easily accessible treatment option with fewer safety concerns that still retains the rapid antidepressant effects is warranted