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We believe that it is not indicated unless significant pain, cosmetic, or pressure symptoms remain after a fair trial of thyroid therapy, and probably steroid therapy, but is appropriate in some cases

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Biomarkers in risk assessment: validity and validation

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Another study found that people with opioid or alcohol use disorder who took GLP-1s had a 40% lower rate of opioid overdose and a 50% lower rate of alcohol intoxication than people who weren't on the medications