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This 68-week trial enrolled 3,417 adults with obesity or overweight with obesity-related complications

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Khatri N, Sumadhura B, Kumar S, Kaundal RK, Sharma S, Datusalia AK

But the pace differs

These increases in the low-dose group were statistically significant compared to baseline, although not to the same extent as the high-dose group

After adjustment for age, sex, hypertension, diabetes, atrial fibrillation and smoking, white matter hyperintensity burden was not significantly associated with poor collaterals (OR 1.278, 95% CI 0.742 2.201, p = 0.376) in regression analysis