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If your goal is repletion, many clinicians start at 500 mg per day for 48 weeks, then move to 250 mg

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[PubMed ID: 18825537]

The precision of this mechanism is a key advantage, as it minimises collateral damage to surrounding tissues. (Peptide Gurus) Summary of findings In summary: FOXO4-DRI has been shown to reduce senescent cell number in animal models and cell culture