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A substantial fraction of Dihexas primary published evidence base originates from the Harding laboratory and direct collaborators
A small case-controlled study comparing 52 DS cases to 52 control cases noted that average maternal serum homocysteine concentration was slightly higher in mothers giving birth to children with DS but this difference was not statistically significant (Mohanty et al 2012)

When starting Vitamin B12 therapy, its not unusual for individuals to grapple with questions like, Feeling worse after my B12 injection, is that natural? This period, often termed as a healing crisis, can manifest through symptoms such as: Enhanced feelings of fatigue, tiredness, and increased sleep requirements Sensations akin to mild flu-like symptoms or body aches Experiences of headaches, nausea, or feelings of being lightheaded A foggy mind and challenges with concentration Mood fluctuations including irritability, anxiety, or a subdued mood Alterations in appetite and digestive patterns Contrary to being seen as an adverse reaction, these symptoms are essentially indicative of the body acknowledging and adapting to the surge of B12
Those degenerative tears can be found on most MRIs but are generally not of clinical relevance (1)
This nutrient partitioning effect directs dietary nutrients toward muscle protein synthesis and away from adipose tissue storage