Data indicate that OC cells release N-acetyl aspartate, which in conjunction with IL-10, synergistically induces the transformation of macrophages into M2-type TAMs that overexpress glutamine synthetase (103)
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Specifically, 20 L of pFeSAN (1 mg/mL) and 20 L of TMB (50 mM) were added into HAc-NaAc buffer (0.1 M, pH 4.0), which contains 0.1 mM GSH, Na + , Ca 2+ , Mg 2+ , K + , Glu, Trp, Arg, Gly, Cys, L-AA, glucose, GOx or BSA
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BMI, Body Mass Index
Within this, cholesterol uptake has turned to be a significant factor in the progression of breast and ovarian cancers, and its targeting can offer promising therapeutical opportunities