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It acknowledges that effective treatment must go beyond surface-level advice and address core biological resistance
Technol Health Care 22(6):857865
These restrictions and warnings demonstrate the FDAs stringent consideration of patient safety in the drug approval process
Generally, chemical hepatotoxicity can be studied using six in vitro experimental systems, namely, isolated perfused liver preparations, liver slices, isolated hepatocytes in suspension, isolated hepatocytes culture and co-culture, cell lines and subcellular fractions [6,12,14,16,17]
In comparison, placebo produced only 3.1% weight loss
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