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Stored in the liver, this powerful antioxidant has been historically difficult to supplement as its easily broken down or degraded in the digestive process

Activation of NRF2 enhances the activity of enzymes such as HO-1 and controls the formation of glutathione (GSH), resulting in protective benefits against oxidative stress [9]

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A study aimed at determining the influence of gender and antioxidant supplementation on exercise-induced oxidative stress reported that, before supplementation, women had higher reduced glutathione and total glutathione compared with men [56]

doi:10.1016/S0006-3495(96)79835-1 91