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Slower nutrient absorption also reduces B-vitamin intake (niacin is a NAD+ precursor)

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Nersessian RSF, da Silva LM, Carvalho MAS, Silveira SQ, Abib ACV, Bellicieri FN, et al

Rare side effects, occurring in fewer than 1 in 1,000 people, may involve a serious allergic reaction (also known as anaphylaxis) and angioedema, which is a type of swelling beneath the skin that can affect the face, lips, tongue or throat