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Statistics and reproducibility All statistics were calculated using GraphPad Prism version 9 with appropriate tests described in the figure legends

PMID 35697072

No adverse effects were reported among patients who received a nonantimicrobial sulfonamide, even among patients who reported a life-threatening allergy

doi: 10.1371/journal.ppat.1000284 6 AllenE

The toxic metabolite your liver produces while breaking down alcohol

In agreement with the noncompetitive behavior of 9 and as determined by structural superposition of the cryo-EM structure and the X-ray NADPH-TGR- complex 17 , inhibitor 9 does not sterically interfere with NADPH binding