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Understanding where each peptide falls on the evidence hierarchy helps researchers set appropriate expectations and make informed decisions

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In 2023 Lilly published results of its phase 2 trial for orforglipron, a once-daily oral drug which achieved up to 14.7% mean weight reduction at 36 weeks, and Pfizer has completed phase 2 trial for its oral drug danuglipron and is now optimising the formulation

23 In glaucoma, the involvement of inducible NOS (iNOS) has also been suggested