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The goal is to develop a healthier lifestyle that inherently supports a lower weight in the long term, not come off the medication as fast as possible

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The meal plans must be capped at 8001,000 calories in total

The lyophilized powder form is optimal when stored desiccated under controlled conditions

Increasing fiber intake, drinking plenty of water, and engaging in regular physical activity can help alleviate constipation

In the event of a serious adverse reaction that the patient and/or treating clinician believed to be caused by or related to the administration of semaglutide or metformin, the medication was discontinued, and the adverse event was reported to the investigator