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Mechanism: It is the first triple hormone receptor agonist to reach Phase 3 clinical trials

Retinol and Retinoic Acid break down fast when they hit light, heat, and air, and Retinoic Acid can be pretty irritating on top of that

[PMC free article: PMC3992250] [PubMed: 20949552] (Among 1198 patients with acute liver failure enrolled in a US prospective study between 1998 and 2007, 133 [11%] were attributed to drug induced liver injury, of which 12 [9%] were due to herbals including usnic acid [2], thermoslim [1], Ma Huang [1], horny goat weed [1], black cohosh [1], Hydroxycut [1] and unspecified herbals [4])

If Lilly uses this approach, FDA can begin reviewing earlier

Neuropeptide Y and peptide YY in association with depressive symptoms and eating behaviours in adolescents across the weight spectrum: from anorexia nervosa to obesity

Serving size: 2 capsules