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(2018) reported that GLP-1 induces either an increase or a decrease of spontaneous firing rate in GLP-1R expressing BNST neurons

The results from the Phase 2 study long-term extension over 3 years showed clinically meaningful and significant effects on slowing both cognitive and functional decline and preserved brain volume in individuals with mild cognitive impairment and two copies of the APOE4 genea group that is often unable to take currently available Alzheimers drugs due to safety concerns

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CD manifests as discontinuous, transmural inflammation affecting any segment of the GI tract, extending from the oral cavity to the anal region