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Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimers disease

J Natl Cancer Inst (1997) 89(1):408

They show how a clinician may think about cycles

The experimental evidence base for DSIP is heterogeneous