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Discontinuation rates due to side effects were highest in the first few months and dropped sharply after the titration phase

However, the study also found that the risk of gallbladder varied between different types of GLP-1 agonists and depended on the therapy duration and dosage

Costill DL

They also suggested that the hair growth cycle may be disrupted due to deficiencies in micronuturients such as: biotin iron zinc Nutritional deficiencies may occur with calorie restriction, resulting in insufficient intake of essential nutrients

GLP-1RA potency, duration, and receptor engagement studies Multi-agonist research context GLP-1 as the reference arm in GIP/GLP-1 and GLP-1/GCG/GIP triple agonist studies What Do Studies Say About GLP-1

The root cause comes down to one of the key mechanisms that makes GLP-1 medications effective in the first place: delayed gastric emptying