317 Interestingly, the phase 2 clinical trial of BIND-014 (a novel PSMA-ADC) in patients with chemotherapy-naive mCRPC suggest that BIND-014 is well tolerated and patients are likely to benefit from the treatment
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(Off label use of FDA compounds is not on unusual but typically its a doctor making those decisions not the patient)
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Clinical trials have shown that metformin alone leads to an average weight loss of about 5 percent of body weight for roughly a third of people who take the drug, including loss of about 12 to 15 pounds in people without diabetes
