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In a study by Son et al., aspartate aminotransferases were demonstrated to be vital in maintaining redox homeostasis in pancreatic ductal adenocarcinoma (PDAC) cells

Materials and Methods Ethical Approval This study was approved by the local ethics committee in Stockholm (2016/1485-32, amendment 2017/779-32) and was conducted according to the Declaration of Helsinki

In addition, other studies have also demonstrated the involvement of TRP channels in paclitaxel-induced pain, which are well known to be predominantly expressed on this subpopulation of DRG neurons

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An Introduction to Systems Biology: Design Principles of Biological Circuits

10.1016/S0006-2952(99)00249-X