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A randomised double-blind placebo-controlled study evaluating eccentric exercises and PRP or saline injection showed no difference in improvement in pain and activity at six months, and a recent meta-analysis concluded that although there may be benefit in using PRP to increase the healing strength in tendo Achilles repair following acute rupture, there was no evidence of any benefit in using PRP in the treatment of Achilles tendinopathy

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Biochemistry 41:22542263 Bae S, Oh K, Kim H, Kim Y, Kim HR, Hwang YI, Lee DS, Kang JS, Lee WJ (2013) The effect of alloferon on the enhancement of NK cell cytotoxicity against cancer via the up-regulation of perforin/granzyme B secretion