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This review synthesizes current research on ferroptosis mechanisms in CHD and emerging clinical intervention strategies
Selim H, Shaheen S, Barakat K, Selim AA
The AORs and p-values were calculated using multiple logistic regression analyses with adjustment for age, physical activity, alcohol intake, body mass index, estimated glomerular filtration rate, diabetes, hypertension, and dyslipidemia
showed that L-carnitine reduces serum CRP levels in rodents infected with the SARS-CoV2 virus and in patients with COVID-19 [20]
These target genes encompass a wide range of antioxidant enzymes and GSH synthesis-related genes, including the key System Xc component SLC7A11
The efficacy of ferroptosis inhibitors (e.g., GPX4 activators) or natural compounds in models of advanced DN (with established glomerular/tubulointerstitial damage) remains untestedwhether these interventions can reverse existing injury or only delay progression is unknown
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