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A four-strain probiotic exerts positive immunomodulatory effects by enhancing colonic butyrate production in vitro

These metabolic changes were paralleled by induction of mitochondrial stress signaling pathways and aberrances of the intestinal stem cell niche, including loss of Paneth cells (9)

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Elevated NETs levels have been reported across multiple malignancies, including diffuse large B-cell lymphoma, esophageal adenocarcinoma, lung adenocarcinoma, and gastric cancer, where they correlate with advanced disease stage and poor prognosis