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If a patient takes both medications daily via pen injections, distinguishing between them becomes harder without understanding the underlying pharmacology

Commercial Feasibility and Total Cost The final selection hinges on economic viability and operational flexibility

This increases side effect risk without proportional benefit

The balance of ROS and antioxidants is important

The flexible dose-adjustment approach allowing patients to escalate or de-escalate doses of the drug on the basis of their HbA1c and gastrointestinal tolerability (PIONEER-7) aimed to individually optimize efficacy and safety of once-daily oral semaglutide in T2D adults uncontrolled with one or two oral glucose-lowering drugs, compared to 100 mg/day of sitagliptin

These medications work in different ways and come with their own benefits and side effects