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Clinical data from semaglutide trials shows average heart rate increases of 2-5 beats per minute, though individual responses vary widely

USA 115 , 26462651 (2018)

Tummolo A, Melpignano L, Carella A, et al

Adequate water intake and balanced electrolyte consumption (sodium, potassium, magnesium) are practical strategies to minimize these symptoms

Liu H, Sridhar VS, Boulet J et al (2022) Cardiorenal protection with SGLT2 inhibitors in patients with diabetes mellitus: from biomarkers to clinical outcomes in heart failure and diabetic kidney disease

Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis