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Ipamorelin has a favorable safety profile, and many users take it for extended periods (6+ months) under medical supervision

But a 4-8 week drug holiday is much shorter than the 28-52 week discontinuation periods in those studies

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Researchers studying semaglutide users have reported an observed association between these medications and optic nerve injuries, although ongoing research continues to evaluate causation, underlying risk factors, and the overall frequency of these events

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