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The authors describe the medication as one component within a multidisciplinary approach, integrated with behavioural support

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doi: 10.1080/09637486.2021.1979478

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Similar confounding might also explain the results for acetazolamide (FAERS COPD ADE signal ROR 2.71 (95% CI 1.504.89)), which can be used as a respiratory stimulant [80]