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IF also activates the nuclear factor erythroid 2related factor 2 (Nrf2) pathway, a master regulator of antioxidant response, leading to the upregulation of superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) [38]

For a more detailed discussion of payments for blood and blood products through APCs, we refer readers to: The CY 2005 OPPS proposed rule (69 FR 50524 and 50525) for a more comprehensive discussion of the blood-specific CCR methodology

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This method is more effective because it bypasses the digestive system