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Data availability The analyzed data in this study are available from the corresponding author upon reasonable request

Test sessions were conducted on the first, third, and eighth injection days (termed injection 1, injection 3, and injection 8, respectively) and on post-treatment days 1 and 3 (see Figure 3A), and training sessions were withheld except for the test sessions

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Sex- and gender-related differences in immunity Immunosenescence differs significantly between sexes and genders, influenced by biological, hormonal, and environmental factors