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Christensen R, Kristensen PK, Bartels EM, Bliddal H, Astrup A

Campisi, Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

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These findings were consistent with Saha et al., who reported that oral NAC (50100 mg/kg) with high fat diet increased IRE1- immunofluorescence labeling and protein expression by western blotting 33

The condition can worsen with continued steroid use, creating a cycle of dependence and rebound [3]