Patients should also consult their diabetes specialist nurse or GP if they experience recurrent injection site reactions despite proper technique
In one study, people who switched to tirzepatide after being on another GLP-1 medication continued to lose weight (about 2.1 kg more in 12 weeks) instead of plateauing
Cost and Availability GLP-1 requires a prescription from a healthcare professional and is generally more expensive than metformin
External resources Once-Weekly Semaglutide for Weight Management: A Clinical Review (PMC) STEP 1 Trial: Once-Weekly Semaglutide in Adults with Overweight or Obesity (NEJM) Effect of Semaglutide 2.4mg on Energy Intake, Appetite, and Gastric Emptying (PMC) Higher Protein Intake May Protect Against Muscle Loss on Anti-Obesity Drugs (Endocrine Society) In case I do not see you, good afternoon, good evening, and good night
2016 [cited 2021 Dec 27];24:227888
Understanding this helps prevent the mistake of attributing success to willpower when biology deserves the credit