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Transforming growth factor-1 (TGF-1) can induce the EMT phenotype in melanoma cells and upregulate the levels of GPX4 and SLC7A11, while gambogenic acid, a xanthone derived from traditional Chinese medicine Gamboge, can promote ferroptosis by inhibiting the SLC7A11/GPX4 pathway in melanoma cells stimulated by TGF-1

Membranes were visualized using WesternBright ECL HRP substrate (Advansta) or SuperSignal West Femto Maximum Sensitivity Substrate (Thermo Fisher Scientific) on a ChemiDoc TM Imaging System (Bio-Rad)

Liposomal glutathione preparations (Tri-Fortify Orange) were provided by Researched Nutritionals, LLC (Los Olivos, CA, USA)

Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors

Surgical management of renal cell carcinoma associated with complex inferior vena caval thrombi