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Clinical trials across the GLP-1 receptor agonist class consistently show an average resting heart rate increase of 1 to 4 beats per minute
GLP-1 receptor agonist medicines such as Wegovy (semaglutide) or Mounjaro (tirzepatide) are designed to be taken once weekly
It may be a signal that the plan needs adjustment
Regulatory acceptance varies by region, with formal approval in certain therapeutic settings and off-label use prevalent in others under clinical supervision
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