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The NRF2-deficient mice did not spontaneously develop skin lesions (Fig

New work demonstrates how one antioxidant inside particular cellular compartments, the mitochondrial metabolite glutathione, helps cancer cells metastasize throughout the body by enabling their survival under low-oxygen conditions

Discussion The highly interwoven acid-base and redox properties of the RSH-RSSR systems can be decomposed into elementary, component equilibria if a) the species-specific protonation constants are determined, and b) the conditional equilibrium constants of the pH-dependent redox equilibria are also quantified

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genetic predisposition, exposure to UVR, pregnancy, and exogenous hormones (i.e., oral contraceptives and hormone replacement therapy)

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