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Barrier repair remains fundamental

2 One study looked at 4-hydroxyisoleucine in rats with an amyotrophic lateral sclerosis-like condition and found better movement and less oxidative stress and cell death through insulin-like growth factor 1 (IGF-1) and GLP-1 pathways, 101 Taken together, these findings suggest that targeting the GLP-1 signaling pathway might be a way to treat amyotrophic lateral sclerosis

Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: Impact on nitric oxide metabolism

Misra et al., 2012a)

Zhang L, Guan Q, Jiang J, Khan MS

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