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Constitutive activation of NRF2, mainly via loss-of-function mutations in the CUL3-adapter KEAP1 or gain-of-function mutations in NFE2L2 , is thought to provide a fitness advantage to tumor cells in confronting metabolic/oxidative stress resulting from dysregulated growth (DeNicola et al, 2011

10.1074/jbc.M110.123323 J

A new strategy to modulate alopecia using a combination of two specific and unique ingredients

doi: 10.3389/fphys.2020.00694 256 SharmaA.TiwariS.DebM

While diet, stress, and lifestyle play important roles, this axis is frequently overlooked in conventional assessments

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