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The flexible dose-adjustment approach allowing patients to escalate or de-escalate doses of the drug on the basis of their HbA1c and gastrointestinal tolerability (PIONEER-7) aimed to individually optimize efficacy and safety of once-daily oral semaglutide in T2D adults uncontrolled with one or two oral glucose-lowering drugs, compared to 100 mg/day of sitagliptin
H.HogrebeM.GrnebergM.DuChesneI.von der HeidenA
doi: 10.1073/pnas.1219451110 35 EverardA.PlovierH.RastelliM.Van HulM.de Wouters d'OplinterA.GeurtsL.et al
Meet the Magpie
Both are chronic conditions that progressively worsen over time
The initial step involves conducting clinical trials to evaluate the safety and efficacy of PLB in PCOS patients and to validate its potential use in humans
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