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Dula (50, 100, and 150 g/kg) substantially reduced the colon's weight, the ratio of weight to length, serum CRP, and LDH levels, boosted histopathological alterations and displayed anti-colitis and anti-inflammatory actions

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These molecules facilitate the closure of ATP-sensitive potassium channels (K ATP ) and the opening of voltage-dependent calcium channels, causing an influx of calcium that triggers the release of insulin granules (Zheng et al., 2024)